Different Airway Inflammatory Phenotypes Correlate with Specific Fungal and Bacterial Microbiota in Asthma and Chronic Obstructive Pulmonary Disease
Table 1
Enrolled subjects’ characteristics.
Parameters
Asthma
COPD
value
EA ()
NEA ()
EC ()
NEC ()
EA vs. NEA
EC vs. NEC
EA vs. EC
NEA vs. NEC
Male (%)
9 (34.62)
8 (42.11)
21 (95.45)
14 (82.35)
0.75‡
0.3‡
0.005‡
<0.001‡
Age (years)
0.308†
0.21※
<0.001†
<0.001※
BMI (kg/m2)
0.455※
0.406†
0.463※
0.617†
ICS dose (μg/d)
0.025※
0.705※
<0.001※
0.025※
Smoking (%)
7 (26.92)
6 (31.58)
15 (68.18)
11 (64.71)
0.751‡
1‡
0.008‡
0.093‡
FEV1 (%predicted)
0.455※
0.216※
<0.001†
<0.001※
FEV1/FVC (%)
0.696※
0.305†
<0.001※
<0.001※
Sputum eosinophils (%)
<0.001※
<0.001※
0.444※
0.739†
Sputum neutrophils (%)
0.001※
<0.001※
0.264※
0.013†
ACT score
—
—
0.954※
—
—
—
CAT score
—
—
—
0.848†
—
—
Data were presented as and unless otherwise stated. The ICS doses were converted to equivalents of fluticasone. †Tested by -test. ‡Tested by Fisher’s exact test. ※Tested by Wilcoxon rank-sum test.
