Effects of Hyperthyroidism on Venous Thromboembolism: A Mendelian Randomization Study

Figure 1

Forest plots for the association of FSH-, TSH-, hyperthyroidism-, and hypothyroidism-associated SNPs with risk of venous thromboembolism. (a) FSH, (b) TSH, (c) hyperthyroidism, and (d) hypothyroidism. In the forest plots, black points represent the log OR for venous thromboembolism per SD increase in FSH, produced using each FSH-associated SNP as an IV. Red points represent the combined causal estimates using all SNPs as an IV on the basis of MR-Egger and IVW methods. Horizontal line represents 95% CI of the estimates. Abbreviations: SNP: single nucleotide polymorphism; TSH: thyrotropin; OR: odds ratio; CI: confidence interval.

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