Effects of Hyperthyroidism on Venous Thromboembolism: A Mendelian Randomization Study

Figure 2

Scatter plots for the association of FSH-, TSH-, hyperthyroidism-, and hypothyroidism-associated SNPs with risk of venous thromboembolism. (a) FSH, (b) TSH, (c) hyperthyroidism, and (d) hypothyroidism. In the scatter plot, -axis represents SNP effects on FSH, TSH, hyperthyroidism, and hypothyroidism (SD), and -axis represents venous thromboembolism risk (log OR and 95% CI). The Mendelian randomization regression slopes of the lines denote the causal estimates utilizing five methods (IVW, MR-Egger, weighted median, simple mode, and weighted mode). Abbreviations: SNP: single nucleotide polymorphism; TSH: thyrotropin; OR: odds ratio; CI: confidence interval.

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