Effects of Hyperthyroidism on Venous Thromboembolism: A Mendelian Randomization Study

Table 3

Univariate Mendelian randomization analysis for the effects of TSH on venous thromboembolism risk.

SNP	EAE	OAE	EAO	OAO	Chr	Exposure			Outcome
						Effect	SE	value	Effect	SE	value
rs1042673	G	A	G	A	17	0.0546	0.0061	3.53E-19	7E-04	0.016	0.9638
rs1045476	A	G	A	G	16	0.049	0.0082	2.29E-09	0.033	0.0203	0.1045
rs1079418	A	G	A	G	6	0.1009	0.0066	9.21E-53	0.0081	0.018	0.6514
rs10814915	T	C	T	C	9	0.0421	0.0061	5.14E-12	0.0278	0.0159	0.0800995
rs10917469	A	G	A	G	1	0.1112	0.0085	4.15E-39	-0.0129	0.0242	0.5936
rs10957494	G	A	G	A	8	0.0402	0.0066	1.12E-09	-0.0028	0.0172	0.8688
rs11159482	T	C	T	C	14	0.0846	0.0129	5.45E-11	0.0032	0.0325	0.9226
rs11255790	C	T	C	T	10	0.041	0.0066	5.23E-10	-0.0073	0.0203	0.717999
rs1157994	G	A	G	A	17	0.09	0.016	1.86E-08	0.0878	0.0395	0.0262102
rs11732089	T	C	T	C	4	0.115	0.0076	1.00E-51	-0.0362	0.0243	0.1366
rs1203944	C	T	C	T	20	0.0509	0.0073	3.11E-12	-0.016	0.0195	0.4119
rs12284404	G	A	G	A	11	0.0667	0.0069	4.18E-22	-0.0021	0.0173	0.9014
rs1265091	T	C	T	C	6	0.0571	0.0086	3.15E-11	-4E-04	0.0238	0.987
rs12893151	C	A	C	A	14	0.0624	0.0078	1.24E-15	0.0342	0.0183	0.0614497
rs13015993	A	G	A	G	2	0.0818	0.0069	2.03E-32	-0.0082	0.0164	0.614899
rs13329353	T	C	T	C	15	0.0614	0.0065	3.52E-21	-0.0016	0.0168	0.9262
rs1663070	C	T	C	T	3	0.0463	0.007	3.73E-11	-0.0029	0.0189	0.8791
rs17020122	T	C	T	C	1	0.1044	0.0114	5.29E-20	0.0164	0.0248	0.5088
rs17477923	T	C	T	C	15	0.0826	0.0069	5.04E-33	0.0015	0.0172	0.9291
rs17767491	A	G	A	G	16	0.0883	0.0065	4.94E-42	0.0095	0.0172	0.5777
rs2127387	A	G	A	G	5	0.1435	0.0062	1.63E-118	0.0015	0.0161	0.9236
rs2439301	G	A	G	A	8	0.0587	0.0076	1.13E-14	0.0125	0.0179	0.4845
rs28502438	T	C	T	C	3	0.0338	0.0061	3.01E-08	0.0382	0.0166	0.0212902
rs30227	C	T	C	T	16	0.0468	0.0063	1.10E-13	-0.0162	0.0164	0.3225
rs334725	A	G	A	G	1	0.1737	0.0147	3.21E-32	0.0077	0.0573	0.8924
rs398745	C	A	C	A	14	0.052	0.0062	4.98E-17	0.0131	0.0164	0.4224
rs4445669	C	T	C	T	11	0.0397	0.0061	7.61E-11	-0.0048	0.0159	0.764599
rs4804413	T	C	T	C	19	0.0532	0.0062	9.43E-18	-0.0134	0.0162	0.4066
rs4933466	A	G	A	G	10	0.0395	0.0063	3.61E-10	-0.007	0.0162	0.666699
rs59381142	G	A	G	A	3	0.058	0.0076	2.32E-14	-0.0316	0.0205	0.1232
rs7329958	C	T	C	T	13	0.0439	0.0065	1.44E-11	0.0077	0.0167	0.644401
rs8015085	A	G	A	G	14	0.0671	0.0077	2.93E-18	0.0071	0.0207	0.7319
rs9298749	C	A	C	A	9	0.0393	0.0064	8.22E-10	-0.0152	0.016	0.3431
rs9381266	T	C	T	C	6	0.0726	0.007	3.34E-25	-0.0046	0.0197	0.8172
rs9497965	T	C	T	C	6	0.0444	0.0062	7.99E-13	-0.0217	0.0168	0.1971
rs963384	T	C	T	C	17	0.0351	0.0063	2.53E-08	0.0117	0.0159	0.4626

Abbreviations: SNP: single nucleotide polymorphism; EAE: effect allele exposure; OAE: other allele exposure; EAO: effect allele outcome; OAO: other allele outcome; Chr: chromosome; SE: standard error.