Research Article
Copy Number Variation and Frequency of rs179008 in TLR7 Gene Associated with Systemic Lupus Erythematosus in Two Mexican Populations
Table 1
Association analysis of CNV of the TLR7 in SLE patients and healthy controls from Yucatán and Central Mexico.
| | Location | CNV | SLE patients (%) | Healthy controls (%) | OR | 95% IC | |
| | Yucatán | ≤ 2 | 86 (86%) | 102 (100%) | 34.36 | 2.02-584.46 | 3.00 -04 | | > 2 | 14 (14%) | N/D | | Central Mexico | ≤ 2 | 145 (96%) | 121 (100%) | 10.85 | 0.60-194.64 | 7.10 -02 | | > 2 | 6 (4%) | N/D | | Yucatán | > 2 | 14 (14%) | — | 3.93 | 1.45-10.61 | 8.40 -03 | | Central Mexico | > 2 | 6 (4%) | | Yucatán/Central Mexico | > 2 | () | () | 2.76 | 1.02-7.46 | 4.40 -03 | | Yucatán/Central Mexico | ≤ 2 | () | () | 0.70 | 0.48-1.02 | 6.61 -02 |
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N/D: no detected.
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