Chinese Herbal Formula Huayu-Qiangshen-Tongbi Decoction Attenuates Rheumatoid Arthritis through Upregulating miR-125b to Suppress NF-κB-Induced Inflammation by Targeting CK2

Figure 3

miR-125b suppresses NF-κB activation through CK2 in LPS-treated MH7A cells. MH7A cells were transfected with miR-125b mimics or miR-125b inhibitor and then treated with 1 μg/mL LPS for 24 h. (a) The mRNA expression of miR-125b was evaluated via qRT-PCR. (b) Human CK2 concentration in the cultured supernatant was measured by using an ELISA assay. (c) The protein expression of NF-κB pathway members including p-p65 and p-IkB-α was evaluated via western blot. , , , and .

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