Research Article

Chinese Herbal Formula Huayu-Qiangshen-Tongbi Decoction Attenuates Rheumatoid Arthritis through Upregulating miR-125b to Suppress NF-κB-Induced Inflammation by Targeting CK2

Figure 4

miR-125b suppresses NF-κB activation through CK2 in LPS-treated MH7A cells. MH7A cells were transfected with miR-125b mimics or cotransfected with miR-125b and pcDNA-IkB-α and then treated with LPS or PDTC. (a) The protein level of p-p65 and p-IkB-α was evaluated via western blot. (b) The cytokine protein levels including TNF-α, IL-1β, and IL-6 in the cellular supernatant were measured by using ELISA assay. , , , and .
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