Isthmin 1 is Expressed by Progenitor-Like Cells in the Lung: Phenotypical Analysis of Isthmin 1⁺ Hematopoietic Stem-Like Cells in Homeostasis and during Infection

Figure 7

Lung ISM1⁺ progenitor-like cells express TLR9, TLR4, and TLR5. (a) Whole lung cells were stained against ISM1, c-kit, and CD45, and TLRs presence were detected. A representative experiment is shown out 3 independent experiments. (b) In vitro stimulation of lung cells with TLR9, TLR4, and TLR5 agonists; ISM1⁺ cells decreased after 4 h of stimulation. Data are means plus SEM independent experiments. Statistical analysis was performed by one-way ANOVA; .

(a)

(b)