The Dectin-1 Receptor Signaling Pathway Mediates the Remyelination Effect of Lentinan through Suppression of Neuroinflammation and Conversion of Microglia

Figure 3

LNT, by modulating the dectin-1 receptor, inhibited LPS-induced microglial cell inflammation in BV2 cells. (a) The protein level of dectin-1 was detected by Western blot. (b) The survival rate of BV2 cells was measured by CCK-8 assay with different concentrations of Lam for 24 h. The protein levels of Iba1 (c), iNOS (d), Arg-1 (e), TNF-α (f), IL-1β (g), IL-10 (h), and BDNF (i) were detected by Western blot. All data are presented as the . Statistical analysis was performed using one-way ANOVA followed by the post hoc Tukey tests. (, , and .)

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