The Dectin-1 Receptor Signaling Pathway Mediates the Remyelination Effect of Lentinan through Suppression of Neuroinflammation and Conversion of Microglia

Figure 6

LNT ameliorated CPZ-induced variations in cytokine expression and glial cell activation by regulating the dectin-1 receptor. (a) Representative images and histogram of quantitative data of GFAP-positive cells, Olig2-positive cells, and Iba1-positive cells in the corpus callosum. Histogram of quantitative data of the protein expression levels of Olig2 (b), Iba1 (c), iNOS (d), Arg-1 (e), TNF-α (f), IL-1β (g), BDNF (h), and IL-10 (i) was detected by Western blot. White arrows indicate representative cells in the treatment group. All data are presented as the . (a). Statistical analysis was performed using one-way ANOVA followed by the post hoc Tukey tests. (, , .)

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