The Contribution of Hepatic Macrophage Heterogeneity during Liver Regeneration after Partial Hepatectomy in Mice

<div>The reduction and restoration of Kupffer cells and the transformation of ly6C<sup>hi</sup> infiltrated macrophages after PHx. (a) C57BL/6 mice were sacrificed at day 1, 2, 4, 6, or 8 after 2/3 PHx or sacrificed immediately after sham operation. The subpopulation of HNPCs was analyzed by FACS with anti-F4/80, anti-CD11b, anti-ly6C, and anti-CCR2 antibodies. The number of (b) F4/80<sup>+</sup> macrophages and (c) F4/80<sup>hi</sup> CD11b<sup>+</sup> KCs in (a) was determined and quantitatively compared. 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Journal of Immunology Research

fig2

Figure 2

Figure 2: The Contribution of Hepatic Macrophage Heterogeneity during Liver Regeneration after Partial Hepatectomy in Mice 