Identification of Common Oncogenic Genes and Pathways Both in Osteosarcoma and Ewing’s Sarcoma Using Bioinformatics Analysis

Figure 1

Identification of DEGs and their biological functions for osteosarcoma. (a) Heatmap showing 329 DEGs between osteosarcoma cells and mesenchymal stem cells. Red represents upregulated genes and green represents downregulated genes. GO including (b) biological process, (c) cell component, and (d) molecular function and (e) KEGG enrichment results depicting underlying biological functions for these DEGs. (f–i) GSEA results based on these DEGs, including cell motility, extracellular matrix, signaling receptor binding, and regulation of cell adhesion.

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