Identification of Common Oncogenic Genes and Pathways Both in Osteosarcoma and Ewing’s Sarcoma Using Bioinformatics Analysis

Figure 3

Identification of DEGs and their biological functions for Ewing’s sarcoma. (a) Heatmap showing 1688 DEGs between Ewing’s sarcoma and mesenchymal stem cells. Red represents upregulated genes and green represents downregulated genes. GO including (b) cell component, (c) molecular function, and (d) biological process and (e) KEGG enrichment results depicting underlying biological functions for these DEGs. (f–i) GSEA results according to these DEGs, including extracellular matrix, collagen-containing extracellular matrix, DNA binding transcription factor activity, and cell substrate adhesion.

(a)

(b)

(c)

(d)

(e)

(f)

(g)

(h)

(i)