Blood Biomarkers Predict Survival Outcomes in Patients with Hepatitis B Virus-Induced Hepatocellular Carcinoma Treated with PD-1 Inhibitors

Table 2

Univariate Cox proportional hazards regression models for progression-free survival.

Variable	Univariate analysis
	HR	95% CI	value
Gender
Male vs. female	1.427	0.52-3.915	0.49
Age
<60 vs. ≥60	1.230	0.454-3.334	0.684
ECOG performance score
≥2 vs. <2	1.733	0.695-4.319	0.238
BMI
<25 vs. ≥25	1.559	0.548-4.440	0.405
Child-Pugh class
B vs. A	2.152	0.697-6.643	0.183
BCLC stage
C vs. B	2.655	0.351-20.097	0.344
CNLC stage
IIIb vs. IIb and IIIa	4.992	1.152-21.631	0.032
PVTT
Yes vs. none	14.290	1.907-107.102	0.010
AFP
≥400 vs. <400 ng/ml	2.394	0.895-8.400	0.082
SII
≥970 vs. <970	12.72	4.863-33.271	< 0.0001
PLR
≥140vs. <140	4.211	1.594-11.126	0.004
NLR
≥5 vs. <5	3.990	1.599-9.959	0.003
LMR
≥1.8 vs. <1.8	0.229	0.092-0.572	0.002