Blood Biomarkers Predict Survival Outcomes in Patients with Hepatitis B Virus-Induced Hepatocellular Carcinoma Treated with PD-1 Inhibitors

Table 5

Univariate Cox proportional hazards regression models for overall survival.

Variable	Univariate analysis
	HR	95% CI	value
Gender
Male vs. female	1.377	0.500-3.791	0.536
Age
<60 vs. ≥60	1.056	0.392-2.843	0.915
ECOG performance score
≥2 vs. <2	1.830	0.721-4.646	0.203
BMI
<25 vs. ≥25	1.589	0.565-4.473	0.380
Child-Pugh class
B vs. A	2.162	0.694-6.738	0.184
BCLC stage
C vs. B	2.164	0.284-16.466	0.456
CNLC stage
IIIb vs. IIb and IIIa	4.088	0.938-17.805	0.061
PVTT
Yes vs. none	14.110	1.882-105.773	0.010
AFP
≥400 vs. <400 ng/ml	2.114	0.801-5.580	0.131
SII
≥970 vs. <970	10.638	3.972-28.492	<0.0001
PLR
≥140vs. <140	3.910	1.483-10.314	0.006
NLR
≥5 vs. <5	4.388	1.726-11.158	0.002
LMR
≥1.8 vs. <1.8	0.278	0.110-0.700	0.007