Helicobacter pylori Infection Elicits Type I Interferon Response in Human Monocytes via Toll-Like Receptor 8 Signaling

Figure 1

Upregulated expressions of TLRs in the THP-1 cells upon H. pylori infection. THP-1 cells were uninfected (mock) and infected with H. pylori J99 or SS1 strains at a MOI of 10 for 16 hours before RNA isolation and qRT-PCR analysis. axis shows the relative fold changes of the expression of the TLR transcripts relative to the β-actin endogenous housekeeping gene. Data is presented as from one experiment run in triplicate and is representative of two independent experiments. Statistical significance was analyzed using Student’s -test (n.s.: not significant; ; ; ).