Comparison of Transcriptomic Signatures between Monkeypox-Infected Monkey and Human Cell Lines

Figure 1

Schematic illustration of the study design. High-throughput data of monkeypox-infected 7-hours of Macaca mulatta kidney epithelial (MK2) cells and monkeypox-infected 6-hours of human immortal epithelial cancer (HeLa) cells were both acquired from the GEO database. The top 5% of differentially expressed genes in the two monkeypox-infected models were determined through a Venn diagram analysis. Results of pathway analyses and functional interpretations were analyzed using DAVID, GO, STRING, and MetaCore.