Circular RNA RHOT1 Regulates miR-142-5p/CCND1 to Participate in Chondrocyte Autophagy and Proliferation in Osteoarthritis

Figure 1

The expression of circRHOT1, miR-142-5p, CCND1, and autophagy markers in OA patients. (a, b) The expression of autophagy markers, including LC3 and beclin1, was measured by qPCR in clinical OA samples () and healthy cases (). (c) The expression of circRHOT1 was detected by qPCR in clinical OA samples () and healthy cases (). (d) The expression of CCND1 was determined by qPCR in clinical OA samples () and healthy cases (). (e) The expression of miR-142-5p was analyzed by qPCR in clinical OA samples () and healthy cases (). (f)–(h) The correlation of circRHOT1, miR-142-5p, and CCND1 was analyzed in clinical OA samples (). , .

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