Identification of an Immune Gene-Based Cisplatin Response Model and CD27 as a Therapeutic Target against Cisplatin Resistance for Ovarian Cancer

Figure 7

The association of CD27 expression with cisplatin response. (a, b) KMplot showed the overall survival rates of high-, medium-, and low-expression groups in TCGA and GSE135820 datasets. (c) The correlation of CD27 expression with cisplatin response scores. The Spearman rho statistic and the corresponding value were estimated. (d) The expression values of CD27 between cisplatin response and nonresponse groups in the GSE23554 (left) and GSE148392 (right) datasets. (e) The correlation of CD27 expression with IC50 values on 19 OV cell lines. The Spearman rho statistic and the corresponding value were estimated. (f) The correlation matrix showed the correlations of CD27 expression with the four genes, PDCD1, CD274, GZMA, and PRF1.

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