Ag85A, As an S2 Vaccine Carrier, Reduces the Toxicity of the S2 Vaccine and Enhances the Protective Ability of Mice against Brucella

Figure 4

The S2-Ag85A vaccine induces immune responses. (a) In the serum and spleen of mice, the levels of IgG expression are significantly elevated in the S2-Ag85A group than that in the S2 group ( value < 0.05). (b) In the serum and spleen of mice, the levels of IgG1 expression are significantly elevated in the S2-Ag85A group than that in the S2 group ( value < 0.05). (c) In the serum and spleen of mice, the levels of IgG2a expression are significantly elevated in the S2-Ag85A group than that in the S2 group ( value < 0.05). compared with the S2 group.

(a)

(b)

(c)