Circulating IL-1β, IL-17, and IP-10 as Potential Predictors of Hepatitis B Virus Infection Prognosis

Table 1

Characteristics of the enrolled subjects.

Characteristics	CHB; ()	SC; ()	Hepatoma; ()	Control; ()
Age^a					0.231
Sex; (male/female)	53/28	50/20	27/15	18/11	0.764
HBsAg+^b	81 (100.00%)	0 (0.00%)	42 (100.00%)	0 (0.00%)	<0.001
HBsAb+^b	0 (0.00%)	70 (100.00%)	0 (0.00%)	29 (100.00%)	<0.001
HBeAg+^b	56 (69.14%)	0 (0.00%)	9 (21.43%)	0 (0.00%)	<0.001
HBeAb+^b	21 (25.93%)	0 (0.00%)	35 (83.33%)	0 (0.00%)	<0.001
HBcAb+^b	81 (100.00%)	70 (100%)	42 (100.00%)	0 (0.00%)	<0.001
HBV DNA (IU/mL)^c	()	NA	()	NA	<0.001
TB (μmol/L)^c	14.7 (12.0–19.5)	13.1 (10.2–16.8)	18.5 (11.9–25.1)	11.9 (8.6–15.3)	<0.001
DB (μmol/L)^c	5.1 (4.0–7.1)	3.9 (2.9–5.1)	8.0 (5.3–13.3)	3.5 (2.5–4.8)	<0.001
IB (μmol/L)^c	10.2 (7.6–13.1)	9.3 (7.2–11.8)	9.3 (6.1–13.9)	8.1 (6.1–10.9)	0.229
ALT (IU/L)^c	61 (35–139)	21 (15–30)	59 (39–106)	20 (14–30)	<0.001
AST (IU/L)^c	46 (27–78)	22 (17–26)	72 (36–137)	23 (20–28)	<0.001
ALP (IU/L)^c	84 (66–109)	71 (61–84)	105 (82–166)	69 (58–82)	<0.001
GGT (IU/L)^c	28 (12–59)	23 (17–41)	71 (39–161)	19 (11–28)	<0.001
TP (g/L)^a					<0.001
ALB (g/L)^a					<0.001
RBC (×10^12/L)^a				NA	<0.001
Hb (g/L)^a				NA	<0.001
WBC (×10^9/L)^a				NA	0.002
PLT (×10^9/L)^a				NA	0.888
NLF/ANLF	35/46	70/0	12/30	29/0	<0.001

Note: Values reported as ^a, ^bfrequency (percentage), and ^cmedian (interquartile) Abbreviations: ALB: Albumin; ALP: Alkaline phosphatase; ALT: Alanine aminotransferase; ANLF: Abnormal liver function; AST: Aspartate aminotransferase; CHB: Chronic hepatitis B; DB: Direct bilirubin; GGT: Gamma-glutamyl transferase; Hb: Hemoglobin; IB: Indirect bilirubin; NA: Not available; NLF: Normal liver function; PLT: Platelets; RBC: Red blood cell; SC: Spontaneous clearance; TB: Total bilirubin; TP: Total protein; WBC: White blood cell.