Circulating IL-1β, IL-17, and IP-10 as Potential Predictors of Hepatitis B Virus Infection Prognosis

Table 2

Circulating cytokine and chemokine levels of the study groups.

Groups	Proinflammatory cytokines			Anti-inflammatory cytokine	Chemokines
	IL-1β	IL-6	IL-17	IL-10	IL-8	IP-10	MCP-1	MIP-1β
CHB; ()	3.69; (2.20–5.30)	15.68; (13.10–28.29)	46.22; (41.07–53.75)	4.86; (4.14–7.82)	49.77; (23.76–203.30)	2456.50; (1682.16–4016.28)	49.60; (34.82–70.83)	228.94; (146.91–452.52)
SC; ()	0.95; (0.50–1.51)	16.88; (14.57–20.60)	90.62; (73.95–115.70)	0.40; (0.40–3.02)	33.28; (24.45–52.27)	921.18; (669.29–1514.12)	59.97; (48.94–81.59)	125.49; (92.67–185.55)
Hepatoma; ()	0.48; (0.48–2.94)	16.93; (4.10–39.42)	0.57; (0.44–41.07)	0.89; (0.40–7.20)	32.86; (7.40–163.93)	444.35; (235.82–1493.47)	12.53; (7.48–52.13)	57.96; (25.19–169.35)
Control; ()	1.13; (0.93–1.88)	5.96; (3.24–11.18)	28.47; (20.74–53.57)	2.57; (1.48–3.63)	30.37; (14.57–44.94)	925.62; (737.16–1286.39)	49.21; (40.92–65.86)	210.33; (70.33–287.92)
	<0.001	<0.001	<0.001	<0.001	0.003	<0.001	<0.001	<0.001

Note: Values are reported as median (interquartile), pg/mL. Comparisons among groups were performed using the Kruskal-Wallis H test. Abbreviations: CHB: Chronic hepatitis B; IL: interleukin; SC: Spontaneous clearance; IP-10: Interferon-γ-inducible protein-10; MCP-1: Monocyte chemoattractant protein-1; MIP-1β: macrophage inflammatory protein-1β.