Circulating IL-1β, IL-17, and IP-10 as Potential Predictors of Hepatitis B Virus Infection Prognosis

Table 3

Multivariate logistic regression analysis between cytokine/chemokine levels and chronic hepatitis B outcomes.

Variables	SC		Hepatoma
	OR (95% CI)		OR (95% CI)
IL-1β	0.052 (0.005–0.534)	0.013	NA ^b
IL-6	– ^a		– ^a
IL-17	1.468 (1.080–1.995)	0.014	0.933 (0.910, 0.957)	<0.001
IL-10	NA^b		NA^b
IL-8	NA^b		– ^a
IP-10	NA^b		NA^b
MCP-1	NA^b		NA^b
MIP-1β	NA^b		NA^b

Note: ^aVariable was not included in the multivariate analysis because of the lack of statistical significance in the univariate analysis. ^bVariable was not included in the logistic regression equation based on the forward LR stepwise method. Abbreviations: CI: Confidence interval; IL: Interleukin; MCP-1: Monocyte chemoattractant protein-1; MIP-1β: Macrophage inflammatory protein-1β; OR: Odds ratio; SC: Spontaneous clearance.