MZF1 Transcriptionally Activated MicroRNA-328-3p Suppresses the Malignancy of Stomach Adenocarcinoma via Inhibiting CD44

Figure 7

miR-328-3p inhibited tumor growth of STAD in vivo. SNU16 cells transfected with NC agomir or miR-328-3p agomir were subcutaneously injected into nude mice for observation of tumor growth. (a) The images of tumor tissues from the NC agomir and miR-328-3p agomir groups. (b) Tumor volume. (c) Tumor weight. (d) qRT-PCR assay was utilized to detect the expression level of miR-328-3p in xenografts. (e) IHC was employed to measure the expression levels of CD44 and Ki67 in xenograft tumors, and TUNEL staining was used to measure apoptotic cells in tumors. All experiments were performed in triplicate. , .

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