A Systematic Pan-Cancer Analysis of YY1 Aberrations and their Relationship with Clinical Outcome, Tumor Microenvironment, and Therapeutic Targets

Figure 1

YY1 gene expression levels in various tumors and pathological stages. (a) The expression level of YY1 gene in various malignancies was investigated by TCGA dataset. (b) The matching normal tissues from the GTEx database were employed as controls for the types of DLBC, THYM, ACC, LAML, LGG, and OV in the TCGA project. The data for the box plot was provided. (c) We compared the expression levels of total YY1 protein among normal tissues and primary tissues of breast cancer, ovarian cancer, colon cancer, clear cell RCC, UCEC, and LUAD based on the CPTAC dataset. (d) According to TCGA dataset, the degree of expressiveness of YY1 gene was analyzed according to the major pathological stages (stage I, II, III, and IV) of KIRC, LIHC, OV, and SKCM. Log-scale uses Log2 (TPM+1). ; ; and .

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