Clinical Features and Prevalence of Spondyloarthritis in a Cohort of Italian Patients Presenting with Acute Nongranulomatous Anterior Uveitis
Table 1
Main characteristics of study population according to SpA diagnosis.
Total ()
SpA- ()
SpA+ ()
value
/median (IQR)
(%)
/median (IQR)
(%)
/median (IQR)
(%)
Age (yrs)
0.05
47 (48)
25 (40)
22 (61)
0.04
Age at uveitis diagnosis (yrs)
0.005
Uveitis diagnostic delay (mo)
3 (0-32)
5 (0-36)
1 (0-23)
0.28
Sex
M
38 (38)
24 (38)
14 (38)
0.94
F
61 (62)
39 (62)
22 (62)
BMI (kg/m2)
0.88
Family history of SpA†
39 (39)
22 (35)
17 (47)
0.23
Current smoker
23 (23)
14 (22)
9 (25)
0.80
Diabetes mellitus
3 (3)
2 (3)
1 (3)
0.91
Dyslipidemia
25 (25)
16 (25)
9 (25)
0.75
Hypertension
13 (13)
9 (14)
4 (11)
0.65
HLA-B27 +
60 (60)
30 (48)
30 (83)
<0.001
Axial SpA
22 (22)
0 (0)
22 (61)
Nd
Peripheral SpA
14 (14)
0 (0)
14 (39)
Nd
IBP (ASAS criteria)
24 (24)
2 (3)
22 (61)
<0.001
Enthesitis
13 (13)
0 (0)
13 (36)
<0.001
Dactylitis
7 (7)
0 (0)
7 (19)
<0.001
IBD
5 (5)
5 (8)
0 (0)
0.22
Psoriasis
10 (10)
7 (11)
3 (8)
0.66
Urethritis/cervicitis
12 (12)
7 (11)
5 (14)
0.68
Peripheral arthritis
19 (19)
0 (0)
19 (53)
<0.0001
Ophthalmic evaluation:
Uveitis
Acute
29 (29)
16 (25)
13 (36)
0.26
Recurrent
70 (71)
47 (75)
23 (64)
Bilateral uveitis
40 (40)
27 (43)
13 (36)
0.51
Hypopyon
2 (2)
0 (0)
2 (6)
0.06
Synechiae
29 (29)
21 (33)
8 (22)
0.24
Cataract
19 (19)
12 (19)
7 (19)
0.96
Legend: SD: standard deviation; IQR: interquartile range; SpA: spondyloarthritis; F: female; M: male; BMI: body max index; HLA: human leukocyte antigen; IBP: inflammatory back pain; ASAS: Assessment of SpondyloArthritis international Society; IBD: inflammatory bowel disease. †Family history of AS, psoriasis, reactive arthritis, uveitis, or IBD in a first-degree relative (father, mother, sisters, brothers, and children) or second-degree relative (maternal and paternal grandparents, aunts, uncles, nieces, and nephews).
