Research Article

Clinical Features and Prevalence of Spondyloarthritis in a Cohort of Italian Patients Presenting with Acute Nongranulomatous Anterior Uveitis

Table 2

Main characteristics of study population according to male sex.

Total males ()SpA- ()SpA+ () value
/median (IQR) (%)/median (IQR) (%)/median (IQR) (%)

Age (yrs)0.08
25 (66)19 (79)6 (43)0.02
Age at uveitis diagnosis (yrs)45 ± 110.02
Uveitis diagnostic delay (mo)5.5 (0-35)5.5 (0-31)9.5 (0-50)0.94
BMI (kg/m2)0.81
Family history of SpA11 (29)7 (29)4 (29)0.97
Current smoker11 (29)8 (35)3 (23)0.75
Diabetes mellitus1 (3)1 (4)0 (0)0.44
Dyslipidemia7 (18)5 (21)2 (14)0.72
Hypertension5 (13)4 (17)1 (7)0.40
HLA-B27 +21 (55)9 (38)12 (86)0.004
Axial SpA9 (64)0 (0)9 (64)Nd
Peripheral SpA5 (13)0 (0)5 (36)Nd
IBP (ASAS criteria)10 (26)1 (4)9 (64)<0.001
Enthesitis5 (13)0 (0)5 (36)0.002
Dactylitis3 (8)0 (0)3 (21)0.02
IBD2 (5)2 (8)0 (0)0.54
Psoriasis4 (11)2 (8)2 (14)0.56
Urethritis/cervicitis5 (13)3 (13)2 (14)0.87
Peripheral arthritis5 (13)0 (0)5 (36)0.002
Ophthalmic evaluation:
Uveitis
 Acute11 (29)8 (35)3 (21)0.44
 Recurrent27 (71)16 (67)11 (79)
Bilateral uveitis17 (45)10 (42)7 (50)0.62
Hypopyon0 (0)0 (0)0 (0)Nd
Synechiae10 (26)7 (29)3 (21)0.60
Cataract7 (18)5 (21)2 (14)0.61

Legend: BMI: body max index; SpA: spondyloarthritis; HLA: human leukocyte antigen; IBP: inflammatory back pain; ASAS: Assessment of SpondyloArthritis international Society; IBD: inflammatory bowel disease. Family history of AS, psoriasis, reactive arthritis, uveitis, or IBD in a first-degree relative (father, mother, sisters, brothers, and children) or second-degree relative (maternal and paternal grandparents, aunts, uncles, nieces, and nephews).