Research Article

Clinical Features and Prevalence of Spondyloarthritis in a Cohort of Italian Patients Presenting with Acute Nongranulomatous Anterior Uveitis

Table 3

Main characteristics of study population according to female sex.

Total females ()SpA- ()SpA+ () value
/median (IQR) (%)/median (IQR) (%)/median (IQR) (%)

Age (yrs)0.27
27 (44)19 (49)8 (36)0.35
Age at uveitis diagnosis (yrs)0.04
Uveitis diagnostic delay (mo)2 (0-24)3 (0-40)1 (0-8)0.18
BMI (kg/m2)0.99
Family history of SpA28 (46)15 (39)13 (59)0.12
Current smoker12 (20)6 (15)6 (27)0.41
Diabetes mellitus2 (3)1 (3)1 (5)0.68
Dyslipidemia18 (30)11 (28)7 (32)0.77
Hypertension8 (13)5 (13)3 (14)0.93
HLA-B27 +39 (64)21 (54)18 (82)0.03
Axial SpA13 (21)0 (0)13 (59)Nd
Peripheral SpA9 (41)0 (0)9 (41)Nd
IBP (ASAS criteria)14 (23)1 (3)13 (59)<0.001
Enthesitis8 (13)0 (0)8 (36)<0.001
Dactylitis4 (7)0 (0)4 (18)0.006
IBD3 (5)3 (8)0 (0)0.41
Psoriasis6 (10)5 (13)1 (5)0.30
Urethritis/cervicitis7 (12)4 (10)3 (14)0.69
Peripheral arthritis14 (23)0 (0)14 (64)<0.001
Ophthalmic evaluation:
Uveitis
 Acute18 (30)8 (21)10 (45)0.04
 Recurrent43 (70)31 (79)12 (55)
Bilateral uveitis23 (38)17 (44)6 (27)0.21
Hypopyon2 (3)0 (0)2 (9)0.06
Synechiae19 (31)14 (36)5 (23)0.29
Cataract12 (20)7 (18)5 (23)0.65

Legend: SD: standard deviation; IQR: interquartile range; BMI: body max index; SpA: spondyloarthritis; HLA: human leukocyte antigen; IBP: inflammatory back pain; ASAS: Assessment of SpondyloArthritis international Society; IBD: inflammatory bowel disease. Family history of AS, psoriasis, reactive arthritis, uveitis, or IBD in a first-degree relative (father, mother, sisters, brothers, and children) or second-degree relative (maternal and paternal grandparents, aunts, uncles, nieces, and nephews).