Clinical Features and Prevalence of Spondyloarthritis in a Cohort of Italian Patients Presenting with Acute Nongranulomatous Anterior Uveitis
Table 3
Main characteristics of study population according to female sex.
Total females ()
SpA- ()
SpA+ ()
value
/median (IQR)
(%)
/median (IQR)
(%)
/median (IQR)
(%)
Age (yrs)
0.27
27 (44)
19 (49)
8 (36)
0.35
Age at uveitis diagnosis (yrs)
0.04
Uveitis diagnostic delay (mo)
2 (0-24)
3 (0-40)
1 (0-8)
0.18
BMI (kg/m2)
0.99
Family history of SpA†
28 (46)
15 (39)
13 (59)
0.12
Current smoker
12 (20)
6 (15)
6 (27)
0.41
Diabetes mellitus
2 (3)
1 (3)
1 (5)
0.68
Dyslipidemia
18 (30)
11 (28)
7 (32)
0.77
Hypertension
8 (13)
5 (13)
3 (14)
0.93
HLA-B27 +
39 (64)
21 (54)
18 (82)
0.03
Axial SpA
13 (21)
0 (0)
13 (59)
Nd
Peripheral SpA
9 (41)
0 (0)
9 (41)
Nd
IBP (ASAS criteria)
14 (23)
1 (3)
13 (59)
<0.001
Enthesitis
8 (13)
0 (0)
8 (36)
<0.001
Dactylitis
4 (7)
0 (0)
4 (18)
0.006
IBD
3 (5)
3 (8)
0 (0)
0.41
Psoriasis
6 (10)
5 (13)
1 (5)
0.30
Urethritis/cervicitis
7 (12)
4 (10)
3 (14)
0.69
Peripheral arthritis
14 (23)
0 (0)
14 (64)
<0.001
Ophthalmic evaluation:
Uveitis
Acute
18 (30)
8 (21)
10 (45)
0.04
Recurrent
43 (70)
31 (79)
12 (55)
Bilateral uveitis
23 (38)
17 (44)
6 (27)
0.21
Hypopyon
2 (3)
0 (0)
2 (9)
0.06
Synechiae
19 (31)
14 (36)
5 (23)
0.29
Cataract
12 (20)
7 (18)
5 (23)
0.65
Legend: SD: standard deviation; IQR: interquartile range; BMI: body max index; SpA: spondyloarthritis; HLA: human leukocyte antigen; IBP: inflammatory back pain; ASAS: Assessment of SpondyloArthritis international Society; IBD: inflammatory bowel disease. †Family history of AS, psoriasis, reactive arthritis, uveitis, or IBD in a first-degree relative (father, mother, sisters, brothers, and children) or second-degree relative (maternal and paternal grandparents, aunts, uncles, nieces, and nephews).