Clinical Features and Prevalence of Spondyloarthritis in a Cohort of Italian Patients Presenting with Acute Nongranulomatous Anterior Uveitis
Table 5
Main characteristics of study population according to HLA-B27 status.
HLA-B27- ()
HLA-B27+ ()
value
/median (IQR)
(%)
/median (IQR)
(%)
Age (yrs)
0.41
24 (62)
28 (47)
0.15
Age at uveitis diagnosis (yrs)
0.049
Uveitis diagnostic delay (mo)
2 (0-24)
3.5 (0-33)
0.41
Sex
M
17 (44)
21 (35)
0.39
F
22 (56)
39 (65)
BMI (kg/m2)
0.08
Family history of SpA†
14 (36)
25 (42)
0.57
Current smoker
14 (36)
9 (15)
0.02
Diabetes mellitus
1 (3)
2 (3)
0.83
Dyslipidemia
11 (28)
14 (23)
0.43
Hypertension
7 (18)
6 (10)
0.25
Axial SpA
3 (8)
19 (32)
0.005
Peripheral SpA
3 (8)
11 (18)
0.14
SpA
6 (15)
30 (50)
<0.0001
IBP (ASAS criteria)
5 (13)
19 (32)
0.01
Enthesitis
3 (8)
10 (17)
0.20
Dactylitis
1 (3)
6 (10)
0.16
IBD
2 (5)
3 (5)
0.93
Psoriasis
4 (10)
6 (10)
0.97
Urethritis/cervicitis
5 (13)
7 (12)
0.86
Peripheral arthritis
4 (10)
15 (25)
0.07
Ophthalmic evaluation:
Uveitis
Acute
13 (33)
16 (27)
0.48
Recurrent
26 (67)
44 (73)
Uveitis laterality
18 (46)
22 (37)
0.35
Hypopyon
0 (0)
2 (3)
0.25
Synechiae
17 (44)
12 (20)
0.01
Cataract
9 (23)
10 (17)
0.43
Legend: HLA: human leukocyte antigen; SD: standard deviation; IQR: interquartile range; M: male; F: female; BMI: body max index; SpA: spondyloarthritis; IBP: inflammatory back pain; ASAS: Assessment of SpondyloArthritis international Society; IBD: inflammatory bowel disease. †Family history of AS, psoriasis, reactive arthritis, uveitis, or IBD in a first-degree relative (father, mother, sisters, brothers, and children) or second-degree relative (maternal and paternal grandparents, aunts, uncles, nieces, and nephews).
