Protein Regulator of Cytokinesis 1 (PRC1) Upregulation Promotes Immune Suppression in Liver Hepatocellular Carcinoma

Figure 7

GSEA analysis of PRC1 co-expressing genes and the prognostic signature of immune system-related genes. (a) Identification of enriched gene sets by GSEA analysis: kinesins; immune system; PLK1, FOXM1, and Aurora B pathway; cell cycle; and RHO GTPase. OS analysis (b) and PFS analysis (c) of the gene signatures which were associated with the immune system according to the GSEA analysis. The left panel showed the curve of risk score, survival status of the patients, and the heat map of the expression profiles of the prognostic genes in the low- and high-risk group. The right upper panel showed the Kaplan-Meier survival analysis of the gene signature. The right lower panel showed the time-dependent ROC analysis of the gene signature.

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