Comprehensive Analysis Identifies PI3K/Akt Pathway Alternations as an Immune-Related Prognostic Biomarker in Colon Adenocarcinoma Patients Receiving Immune Checkpoint Inhibitor Treatment

Figure 5

(a) GSEA comparison of upregulated and downregulated genes in the PI3K/Akt-MT and PI3K/Akt-WT groups. The enrichment score greater than 0 indicates that the pathway is upregulated in the PI3K/Akt-MT group, and the enrichment score less than 0 indicates that the pathway is downregulated in the PI3K/Akt-MT group. The color of the pathway name is consistent with the color of the broken line in the figure; value less than 0.05 is statistically significant. (b) The potential mechanism of PI3K/Akt-MT patients with colorectal cancer receiving ICI had a better prognosis.

(a)

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