Aerosol Inhalation of Heat-Killed Clostridium butyricum CGMCC0313-1 Alleviates Allergic Airway Inflammation in Mice

Figure 1

Aerosol inhalation of HKCB, oral HKCB administration, or oral CB administration alleviated allergic airway inflammation and mucus hypersecretion. (a) Experimental protocol. (b) Total inflammatory cell count in the BALF. (c) The percentages of differential inflammatory cells in the BALF. (d) HE staining of the lung tissues (magnification 200x). (e) Inflammation scores. (f) PAS staining of the lung tissues (magnification 200x). (g) Mucus scores. versus the NC group; ^#, ^##, and ^### versus the OVA group. i.p.: intraperitoneally; a.i.: aerosol inhalation; CB: Clostridium butyricum; HKCB: heat-killed CB; HE: hematoxylin-eosin; PAS: periodic acid-Schiff; BALF: bronchoalveolar lavage fluid.

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