Research Article

lncRNA SNHG15 as a ceRNA modulates Osteoclast Differentiation, Proliferation, and Metastasis by Sponging miR-381-3p/NEK2 Axis

Figure 1

Induction of osteoclasts and the expression of lnc SNHG15 and miR-381-3p in osteoclasts. (a) TRAP staining observed osteoclast of THP-1 cells induced by RANKL; (b–h) RT-qPCR detected the expression of SNHG15, miR-381-3p, miR-141-3p, miR-451b, miR-183-5p, miR-18a-5p, and miR-506-5p; (i) Western blot detected the proteins expression of osteoclast markers CTSK, MMP-9, NFAT2, and TRAP. Compared with PMA group: , , and .
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