Integrated Single-Cell and RNA Sequencing Analysis Identifies Key Immune Cell and Dendritic Cells Associated Genes Participated in Myocarditis

Figure 5

Comprehensive analysis of scRNA-seq data of myocarditis. (a) Mapping of cell clusters using an unbiased nonlinear dimension reduction of UMAP cluster based on scRNA-seq data. (b) Annotating cell types. Nine major cell types were annotated based on the canonical cell markers. (c) A total of 9136 marker genes were aggregated into 26 clusters, and the top 5 marker genes in each cell type were exhibited. (d) The expression of the top 5 marker genes in each cell type was visualized by bubble plot. (e) The distribution of the most abundantly expressed marker gene in each cell type was visualized on the UMAP plot. (f) Relative distribution of 9 cell types in the myocarditis group and the control group.

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