Expression Analysis of Ligand-Receptor Pairs Identifies Cell-to-Cell Crosstalk between Macrophages and Tumor Cells in Lung Adenocarcinoma

Figure 4

The crosstalk between macrophages and lung adenocarcinoma cells. (a) The network of selected upregulated ligand-receptor pairs from macrophages to tumor cells (blue round rectangles: ligands; yellow ellipse shapes: receptors; line width is consistent with the correlation coefficient between the ligand and receptor). (b) The network of selected upregulated ligand-receptor pairs from tumor cells to macrophages (blue round rectangles: ligands; yellow ellipse shapes: receptors; line width is consistent with the correlation coefficient between the ligand and receptor).

(a)

(b)