Expression Analysis of Ligand-Receptor Pairs Identifies Cell-to-Cell Crosstalk between Macrophages and Tumor Cells in Lung Adenocarcinoma

Figure 5

(a) UMAP plot of tumor-associated macrophages (4 subtypes identified). (b) Scatter plot showing M1 and M2 polarization scores for each color-coded subtypes of tumor-associated macrophages. (c) Scatter plot showing pro- and anti-inflammatory scores for each color-coded subtypes of tumor-associated macrophages. (d) Bubble plot showing selected ligand-receptor interactions between tumor cells and subtypes of tumor-associated macrophages. value is indicated by circle size, with the scale to the right.

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