Interferon-Induced Transmembrane Protein 3 rs34481144 C/T Genotype and Clinical Parameters Related to Progression of COVID-19

Table 1

Comparison laboratory parameters between deceased and recovered patients infected with COVID-19.

Variables	Deceased patients (n = 1,149)	Recovered patients (n = 1,342)	P-value
Mean age ± SD	59.3 ± 10.9	50.9 ± 12.9
Gender (male/female)	611/538 (53.2/46.8%)	697/645 (51.9/48.1%)	0.535
ALT, IU/L (mean ± SD) (reference range: 5–40)	44.5 ± 23.9	33.2 ± 24.3
AST, IU/L (mean ± SD) (reference range: 5–40)	36.9 ± 13.0	31.3 ± 15.7
ALP, IU/L (mean ± SD) (reference range: up to 306)	201.9 ± 66.3	171.0 ± 90.6
Cholesterol, mg/dL (mean ± SD) (reference range: 50–200)	116.6 ± 38.9	121.8 ± 36.3
TG, mg/dL (mean ± SD) (reference range: 60–165)	116.6 ± 41.7	131.5 ± 61.5
LDL, mg/dL (mean ± SD) (reference range: up to 150)	70.2 ± 35.6	107.1 ± 49.3
HDL, mg/dL (mean ± SD) (reference range: >40)	30.6 ± 10.9	34.4 ± 11.6
WBC, 10^9/L (mean ± SD) (reference range: 4,000–10,000)	7,544.4 ± 2,663.4	7,717.4 ± 2,897.6	0.347
CRP, mg/L (mean ± SD) (reference range: <10 mg/L Negative)	67.3 ± 21.4	56.9 ± 20.9
ESR, mm/1st hr (mean ± SD) (reference range: 0–15)	54.5 ± 15.6	46.5 ± 15.3
FBS, mg/dL (mean ± SD) (reference range: 70–100)	110.7 ± 42.9	105.6 ± 41.3
Platelets × 1,000/cumm (mean ± SD) (reference range: 140,000–400,000)	186 ± 76	185 ± 65	0.206
Uric acid, mg/dL (mean ± SD) (reference range: 3.6–6.8)	3.9 ± 1.2	5.6 ± 1.4
Cr, mg/dL (mean ± SD) (reference range: 0.6–1.4)	1.2 ± 0.3	0.7 ± 0.2
T3, ng/dL (mean ± SD) (reference range: 2.3–4.2)	3.1 ± 1.2	2.5 ± 0.8	0.061
T4, mcg/dL (mean ± SD) (reference range: 5.6–13.7)	8.9 ± 4.6	8.3 ± 3.3	0.091
TSH, mu/L (mean ± SD) (reference range: 0.4–4.5)	3.5 ± 1.4	3.3 ± 1.2	0.384
25-Hydroxy vitamin D, ng/mL (mean ± SD) (sufficiency: 21–150)	25.3 ± 10.1	35.9 ± 13.4
Real-time PCR Ct values	13.1 ± 5.7	28.1 ± 8.1

ALT, alanine aminotransferase; AST, aspartate aminotransferase; ALP, alkaline phosphatase; TG, triglyceride; LDL, low-density lipoprotein; HDL, high-density lipoprotein; WBC, white blood cells; CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; FBS, fasting blood glucose; T3, triiodothyronine; T4, thyroxine; TSH, thyroid-stimulating hormone; Ct, cycle threshold; SD, standard deviation; Cr, creatinine. Statistically significant (<0.05).