Exosome Derived from Human Umbilical Cord Mesenchymal Cell Exerts Immunomodulatory Effects on B Cells from SLE Patients

<div>hucMSCs-Exo promoted B cell apoptosis, inhibited proliferation, and prevented overactivation and inflammation. (a) Different concentrations of Exo were cocultured with B cells from SLE. (b) B cell apoptosis was determined using Annexin V-FITC kit (c) B cell proliferation was determined using the CFSE kit. (d) The expression of B cell activation marker CD69. (e) Cytokine expression levels after coculture with hucMSCs and exosomes compared with control. Exosomes were isolated from hucMSC. 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Journal of Immunology Research

fig3

Figure 3

Figure 3: Exosome Derived from Human Umbilical Cord Mesenchymal Cell Exerts Immunomodulatory Effects on B Cells from SLE Patients 