Research Article
Immunohistochemical Features of MMP-9 and pSTAT1 in Granuloma Annulare and Sarcoidosis: A Comparative Study of 62 Cases
Figure 2
MMP-9 expression in granuloma annulare and sarcoidosis biopsies. (a) IHC staining and segmentation of biopsy section of patients with GA, the high-power photo shows that MMP-9 predominantly stain the elastic fibers (EFs) in GA biopsy. (b) IHC staining and segmentation of biopsy section of patients with sarcoidosis, the high-power photo shows that MMP-9 predominantly stains the histiocytes in sarcoidosis biopsy. Lower-power photo, ; high-power photo, . (c) Quantification of IHC staining for MMP-9 in patients with GA and sarcoidosis. (d) Quantification of IHC staining for MMP-9 in EFs in patients with GA and sarcoidosis. MMP-9 is mainly expressed in EFs in GA while histiocytes in sarcoidosis.
(a) |
(b) |
(c) |
(d) |