miR-21-5p Inhibits Ferroptosis in Hepatocellular Carcinoma Cells by Regulating the AKT/mTOR Signaling Pathway through MELK

Figure 3

miR-21-5p targets MELK, and miR-21-5p can suppress the expression of MELK, thereby inhibiting tumor progression: (a) targeted binding sites of miR-21-5p and MELK predicted by starBase; (b) dual-luciferase reporter gene experiment verifying the targeted relationship between miR-21-5p and MELK; (c) Western blot for the level of MELK; (d) CCK8 for cell viability; (e) clonogenic assay for cell proliferation; (f) transwell assay for invasion and migration; (g) EdU staining for cell proliferation. , , .

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