Research Article

The Potential Diagnostic Biomarkers for the IgG Subclass in Coal Workers’ Pneumoconiosis

Table 1

Participants’ characteristics.

CWPs ()DEWs ()HCs () value

Age (years)0.273
BMI (kg/m2)0.635
Smokers (, %)81 (77.88%)77 (70.64%)57 (77.03%)0.642
Drinking status (, %)13 (12.50%)#30 (27.52%)14 (18.92%)0.022
Hypertension (, %)16 (15.38%)12 (11.01%)8 (10.81%)0.548
White blood cells, ×109/mL6.5 (5.4, 7.9)6.0 (5.4, 7.2) #6.8 (5.8, 8.1)0.031
Neutrophils, ×109/mL3.9 (3.2, 5.2)3.6 (2.9, 4.3)3.9 (3.5, 4.8)0.022
Lymphocytes, ×109/mL1.7 (1.4, 2.2)1.9 (1.5, 2.3)2.1 (1.7, 2.6) #0.005
Exposure time, years28 (20, 30)24 (22, 26)NA0.290
FVC, predicted %#<0.001
FEV1, predicted %#<0.001
FEV1/FVC, %68.8 (58.0, 76.3)#84.2 (76.2, 88.2) #75.3 (72.1, 79.0)<0.001

values were calculated by the chi-square test, Kruskal–Wallis test, one-way analysis, Mann–Whitney test, as appropriate. BMI: body mass index; FVC: forced vital capacity; FEV1: forced expired volume in the first second. #Compared with healthy controls, adjusted . Compared with DEWs, adjusted .