Irradiation Attenuates Systemic Lupus Erythematosus-Like Morbidity in NZBWF1 Mice: Focusing on CD180-Negative Cells

Figure 2

Irradiation prevents proteinuria levels in NZBWF1 mice. (a) Comparison of the urinary protein levels between paired sham-irradiated and 4 Gy-irradiated mice 15 weeks after treatment (n = 13 paired mice, Group A). (b) Urinary protein levels in sham-irradiated and irradiated mice. Open and solid bars indicate sham-irradiated and 4 Gy-irradiated mice, respectively (n = 13 in each group, Group A). (c) Urinary protein levels at 6 (n = 50 in each group), 12 (n = 49 vs. 50), 24 (n = 35 vs. 49), and 36 (n = 9 vs. 24) weeks after treatment (Group B) are presented as the mean value ± standard error. (d) Duration from sham-irradiation or irradiation to the development of level 3+ urinary protein (n = 50 in each group, Group B). Open and solid bars indicate sham-irradiated and irradiated mice, respectively. Each group consisted of 50 mice (Group B). Data are presented as mean± standard error. The presents significant difference at and .

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