Immunoinformatics Approach to Design a Chimeric CD70-Peptide Vaccine against Renal Cell Carcinoma

Figure 2

The outcomes from diverse structure validation tools affirmed the reliability and precision of the CD70^(epitopes)−CPP-TNF^{(Whole sequence)} (Homo sapiens) vaccine construct. (a) The 3D model of the CD70^(epitopes)−CPP-TNF^{(Whole sequence)} (Homo sapiens) vaccine construct was developed. (b) The ProSA-web z-score plot displayed a Z-score = −7.62. (c) The Ramachadran plot exhibited 89.5% of residues in the most favored regions. (d) The ERRAT overall quality factor exceeded 86%. (e) Postrefinement, the verify 3D indicated a score of 70.42% for the model.

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