PM2.5 Causes Increased Bacterial Invasion by Affecting HBD1 Expression in the Lung

Figure 2

Effect of PM2.5 coculture on cell activity. (a–f) Microscopic morphological changes in HBE after exposure to different concentrations of atmospheric particulate matter PM2.5 at 24 hr. The CCK-8 method was used to detect cell viability at different concentrations of atmospheric particulate matter PM2.5 cocultured with HBE cells for different times (n = 3). (g) A concentration gradient of 0, 25, 50, 100, 150, 200 μg/mL of PM2.5 was set within each time point. (g1–g5) represents PM2.5 treatment for 2, 6, 12, 24, and 48 hr, respectively (n = 3). , , vs. NC (t test) in this figure.

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