Interleukin-18 Gene Polymorphisms and Rheumatoid Arthritis Susceptibility: An Umbrella Review of Meta-Analyses

Table 3

Study quality assessment results.

Study	(1) Were the search methods reported	(2) Was the search comprehensive	(3) Were the inclusion criteria reported	(4) Was selection bias avoided	(5) Were the validity criteria reported	(6) Was validity assessed appropriately	(7) Were the methods used to combine studies reported	(8) Were the findings combined appropriately	(9) Were the conclusions supported by the reported data	(10) What was the overall scientific quality of the overview
Cai et al. [20]	Yes	Yes	Yes	Unclear	Yes	Not performed	Yes	Yes	Yes	Low
Chen et al. [21]	Yes	Yes	Yes	Unclear	Unclear	Not performed	Yes	Yes	Yes	Low
Ji and Lee [22]	Yes	Yes	Yes	Unclear	Unclear	Not performed	Yes	Yes	Yes	Low
Li et al. [23]	Yes	Yes	Yes	Unclear	Yes	Not performed	Yes	Yes	Yes	Low
Pan et al. [24]	Yes	Yes	Yes	Unclear	Unclear	Not performed	Yes	Yes	Yes	Low
Song et al. [25]	Yes	Yes	Yes	Unclear	Yes	Not performed	Yes	Yes	Yes	Low
Wen et al. [26]	Yes	Yes	Yes	Unclear	Unclear	Not performed	Yes	Yes	Yes	Low