Research Article

Exosomes Derived from Schistosoma japonicum Cystatin-Treated Macrophages Attenuated CLP-Induced Sepsis in Mice

Figure 6

Treatment with Sj-Cys-EXO significantly induced macrophage polarization from M1 to M2 in liver, lung, and kidney of mice with CLP-induced sepsis identified by measuring protein expression of M1 marker iNOS and M2 marker Arg-1 in liver (a), lung (c), and kidney (e) tissues using ELISA, or measuring mRNA expression levels of these markers in liver (b), lung (d), and kidney (f) tissues by RT-qPCR. n = 5 per group. Results are expressed as mean ± SD. , , .
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