Disturbances in the IgG Antibody Profile in HIV-Exposed Uninfected Infants Associated with Maternal Factors

Figure 2

IgG antibody concentrations in HEU infants do not change during the first year of life. Plasma concentrations of IgG1 (a), IgG2 (b), IgG3 (c), IgG4 (d), IgM (e), IgA (f), and IgE (g) were quantified using multianalyte flow assays in HEU infants during their first year of life. The 0-month group comprised n = 54, the 2–3 months group comprised n = 43, the 4–5 months group comprised n = 9, and the 6–12 months group comprised n = 46. Boxes indicate medians and interquartile ranges, with bars indicating percentiles 5 and 95. The sparse data points indicate observations outside these percentiles. Significant differences between groups were assessed using the Kruskal‒Wallis test with Dunn´s post hoc test; , and .

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