Protein Expression of TLR2, TLR4, and TLR9 on Monocytes in TB, HIV, and TB/HIV

Table 1

Study participants demographic and clinical characteristics.

Variables	HC (n = 39)	HIV (n = 35)	TB (n = 34)	TB/HIV (n = 12)
Age in years, median	28	33	30	41
Male sex at birth (%)	58.3	42.4	69.2	50
Body mass index	21.9	20.6	18.3	19.6
BCG scar present (%)	42	20	40	42
PTB (%)	N/A	N/A	89	70
HIV clinical stages I and II (%)	N/A	83.3	N/A	0
HIV viral load, median (IQR)	N/A	5.3 × 10^4 (1–18 × 10^4)	N/A	3.6 × 10^5 (LDL^#−2 × 10^6)
Absolute CD4, median (IQR)	N/A	270 (94–599)	N/A	210 (85–289)
CCL2^ǂ	129	148	114	136
CCL3	UD	UD	135	UD
CCL4	UD	UD	138	79
CXCL10 (IP10)	39	107	234	125
TNFα	1.2	2.4	2.7	2.4
IFNγ	UD	2.75	12.5	3.69
IL6	0.69	0.53	7.66	2.45
IL10	1.6	6.14	19.1	7.37

^ǂPlasma biomarkers in ug/ml and UD, undetectable, ^#48 copies/ml, sample size of 24, and sample size of 7.