Journal of Immunology Research

Immunological Aspect on Late Allograft Dysfunction


Publishing date
05 Jul 2013
Status
Published
Submission deadline
15 Feb 2013

Lead Editor

1Research Institute of Nephrology, Jinling Hospital, Medical School, Nanjing University, Nanjing 210093, China

2Transplantation Research Center, Brigham and Women's Hospital and Children's Hospital Boston, Harvard Medical School, Boston, MA 02215, USA

3Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA


Immunological Aspect on Late Allograft Dysfunction

Description

Organ transplantation is a preferred choice of treatment for end-stage organ failure. With the introduction of new immunosuppressants, the short-term allograft survival has been greatly improved over the last decades; however, long-term graft survival remains unsatisfactory and patients continue to lose their transplants to chronic rejection over time. Many factors affect the long-term graft survival; among them, immunological factor is the leading cause of late grafts loss, which includes both T-cell-mediated and alloantibody-mediated mechanisms in graft damage. A thorough understanding of these mechanisms is quintessential to further improve transplant outcomes in the clinic.

We therefore solicit original research articles, reviews, and perspectives focusing on the immunological mechanisms in late allograft dysfunction; those articles entail studies in renal, liver, heart, lung, intestinal, and other organ transplantation, and both clinical and experimental studies are welcome. These articles will be published in a special issue in the Journal of Clinical and Developmental Immunology. Potential topics include, but are not limited to:

  • Immunological mechanisms of late phase of graft loss
  • Complications and immunological features of chronic rejection
  • Tissue-infiltrating lymphocytes affecting chronic rejection in late phase of transplantation
  • Immune monitoring and biomarkers in late phase of transplantation
  • Role of cellular- and antibody-mediated immune responses in late graft loss
  • Role of T regulatory cells in chronic allograft dysfunction
  • Animal models of late graft dysfunction
  • Evidence-based management of late allograft dysfunction
  • Emerging new approaches in treatment of late graft dysfunction

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/jir/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/jir/iaad/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2014
  • - Article ID 625031
  • - Editorial

Immunological Aspect on Late Allograft Dysfunction

Qiquan Sun | Akinlolu O. Ojo | Xian C. Li
  • Special Issue
  • - Volume 2014
  • - Article ID 549315
  • - Review Article

Transplant Glomerulopathy: The Interaction of HLA Antibodies and Endothelium

William Hanf | Claudine S. Bonder | P. Toby H. Coates
  • Special Issue
  • - Volume 2014
  • - Article ID 582902
  • - Research Article

Capillary Dilation and Rarefaction Are Correlated with Intracapillary Inflammation in Antibody-Mediated Rejection

Xue Li | Qiquan Sun | ... | Zhihong Liu
  • Special Issue
  • - Volume 2014
  • - Article ID 828732
  • - Clinical Study

The Effect of Combination Therapy with Rituximab and Intravenous Immunoglobulin on the Progression of Chronic Antibody Mediated Rejection in Renal Transplant Recipients

Gun Hee An | Jintak Yun | ... | Chul Woo Yang
  • Special Issue
  • - Volume 2013
  • - Article ID 849835
  • - Review Article

Incidence and Clinical Significance of De Novo Donor Specific Antibodies after Kidney Transplantation

Sophia Lionaki | Konstantinos Panagiotellis | ... | John N. Boletis
  • Special Issue
  • - Volume 2013
  • - Article ID 809847
  • - Clinical Study

APACHE IV Is Superior to MELD Scoring System in Predicting Prognosis in Patients after Orthotopic Liver Transplantation

Yueyun Hu | Xianling Zhang | ... | Ailing Hu
  • Special Issue
  • - Volume 2013
  • - Article ID 509259
  • - Research Article

Molecular Profiling of Acute and Chronic Rejections of Renal Allografts

Hřibová Petra | Honsová Eva | ... | Viklický Ondřej
  • Special Issue
  • - Volume 2013
  • - Article ID 758159
  • - Research Article

Protective Effects of HBSP on Ischemia Reperfusion and Cyclosporine A Induced Renal Injury

Yuanyuan Wu | Junlin Zhang | ... | Bin Yang
  • Special Issue
  • - Volume 2013
  • - Article ID 460316
  • - Research Article

The Diagnostic Value of Transcription Factors T-bet/GATA3 Ratio in Predicting Antibody-Mediated Rejection

Xue Li | Qiquan Sun | ... | Zhihong Liu
  • Special Issue
  • - Volume 2013
  • - Article ID 859761
  • - Review Article

Late and Chronic Antibody-Mediated Rejection: Main Barrier to Long Term Graft Survival

Qiquan Sun | Yang Yang
Journal of Immunology Research
 Journal metrics
Acceptance rate40%
Submission to final decision65 days
Acceptance to publication30 days
CiteScore3.330
Impact Factor3.404
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