Journal of Immunology Research

Alloreactivity-Based Medical Conditions


Publishing date
27 Sep 2013
Status
Published
Submission deadline
10 May 2013

1Sheikh Zayed Institute for Pediatric Surgical Innovation, Children's National Medical Center, Washington, DC 20010, USA

2Department of Anatomy and Cell Biology, University of Kansas Medical Center, Kansas City, KS 66160, USA

3Department of Pediatrics, Children's Hospital and Regional Medical Center, University of Washington, Seattle, WA 98109, USA

4Department of Physiology and Immunology, University of Rijeka, Rijeka, Croatia


Alloreactivity-Based Medical Conditions

Description

Alloreactivity underlies a broad spectrum of medical conditions created by introduction of alloantigens through medical intervention (such as transfusion or tissue transplantation) or during pregnancy. Knowledge of alloreactivity as a basis of many medical conditions is beginning to emerge, and there is a need to increase awareness of the immunological basis of these conditions that include, but are not limited to, graft rejection, graft versus host disease, reaction to blood (products) or biopharmaceuticals, immunopathology of pregnancy (implantation failure, recurrent pregnancy loss, preeclampsia/eclampsia), and fetal and neonatal diseases (thrombocytopenia, hemolytic anemia, hemochromatosis, biliary atresia, glomerulopathy).

Diverse immunologic components, including T cells, antibodies (B cells), and NK cells, promote alloreactivity, and this complexity makes the pathogenesis of these conditions distinct and unique. We invite authors to submit original research and review papers that uncover new medical conditions caused by alloreactivity, define molecular mechanisms of pathogenesis, or offer new therapeutic approaches for alloreactivity-based medical conditions. Potential topics include, but are not limited to:

  • Identification of antigens targeted by alloreactive immune cells or molecules
  • Elucidating cellular and/or molecular mechanisms of alloreactivity-based conditions
  • Uncovering novel conditions caused by alloreactivity
  • Molecular markers of development and/or prognosis of alloreactive condition
  • Defining conditions predisposing for alloreactivity
  • New animal models of alloreactive conditions
  • Role of inflammation in pathogenesis of alloreactive conditions
  • Novel mechanisms of induction of tolerance to alloantigens
  • Development of cellular chimerism

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/jir/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/jir/abmc/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2013
  • - Article ID 567084
  • - Editorial

Alloreactivity-Based Medical Conditions

Stanislav Vukmanovic | Margaret G. Petroff | ... | Daniel Rukavina
  • Special Issue
  • - Volume 2013
  • - Article ID 542152
  • - Review Article

Mucins Help to Avoid Alloreactivity at the Maternal Fetal Interface

Arnela Redzovic | Gordana Laskarin | ... | Daniel Rukavina
  • Special Issue
  • - Volume 2013
  • - Article ID 852395
  • - Review Article

Regulatory T Cells in the Immunodiagnosis and Outcome of Kidney Allograft Rejection

O. Franzese | A. Mascali | ... | N. Di Daniele
  • Special Issue
  • - Volume 2013
  • - Article ID 972705
  • - Clinical Study

Significance of Semiquantitative Assessment of Preformed Donor-Specific Antibody Using Luminex Single Bead Assay in Living Related Liver Transplantation

Atsushi Yoshizawa | Hiroto Egawa | ... | Sinji Uemoto
  • Special Issue
  • - Volume 2013
  • - Article ID 937846
  • - Clinical Study

The Association of CD81 Polymorphisms with Alloimmunization in Sickle Cell Disease

Zohreh Tatari-Calderone | Ryad Tamouza | ... | Stanislav Vukmanovic
  • Special Issue
  • - Volume 2013
  • - Article ID 545621
  • - Review Article

New Allogeneic Hematopoietic Stem Cell Transplantation Method: Hematopoietic Stem Cell Transplantation Plus Thymus Transplantation for Intractable Diseases

Naoki Hosaka
  • Special Issue
  • - Volume 2013
  • - Article ID 986859
  • - Research Article

Glucocorticoid-Induced TNFR-Related Protein Stimulation Reverses Cardiac Allograft Acceptance Induced by CD40-CD40L Blockade

Kenneth T. Krill | Keri Csencsits-Smith | ... | D. Keith Bishop
  • Special Issue
  • - Volume 2013
  • - Article ID 267156
  • - Review Article

Nuclear Antigens and Auto/Alloantibody Responses: Friend or Foe in Transplant Immunology

Toshiaki Nakano | Chao-Long Chen | Shigeru Goto
Journal of Immunology Research
 Journal metrics
Acceptance rate45%
Submission to final decision61 days
Acceptance to publication37 days
CiteScore5.100
Impact Factor3.327
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